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NEW YORK–(BUSINESS WIRE)–Regulatory News:

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Cellectis S.A. (Paris:ALCLS) (NASDAQ:CLLS) (Euronext Growth: ALCLS – Nasdaq: CLLS), a clinical-stage biopharmaceutical aggregation focused on developing immunotherapies based on gene-edited allogeneic CAR T-cells (UCART), today appear its after-effects for the three-month aeon concluded September 30, 2017 and for the nine-month aeon concluded September 30, 2017.

Balance Alarm Details

Cellectis will host an balance alarm on November 14, 2017 at 8:30am Eastern Time to altercate its banking after-effects and accommodate a accustomed business update.

Dial-In Numbers:Live PARTICIPANT Dial-In (Toll-Free US & Canada): 877-407-3104Live PARTICIPANT Dial-In (International): 1 201-493-6792

Replay Information:Conference ID #: 13625168Replay Dial-In (Toll Free US & Canada): 877-660-6853Replay Dial-In (International): 1 201-612-7415Expiration Date: 11/28/17

Webcast URL (Archived for 6 months): http://cellectis.equisolvewebcast.com/q3-2017

____________________1 Banknote position includes cash, banknote agnate and accustomed banking assets.

Third Division 2017 and Recent Highlights

Cellectis – Therapeutics

UCART123: Cellectis’ TALEN® gene-edited, allogeneic CAR T artefact applicant in AML and BPDCN Patients

As of November 6, 2017, Cellectis appear that the U.S. Food and Drug Administration (FDA) has aerial the analytic hold, ahead appear on September 4, 2017, on both Appearance 1 trials of UCART123 artefact applicant in astute myeloid leukemia (AML) and blastic plasmacytoid blooming corpuscle bump (BPDCN). In affiliation with the appropriation of the analytic hold, Cellectis agreed with the FDA to assertive revisions to be implemented in Appearance 1 UCART123 protocols. Cellectis is currently alive with the lath from Weill Cornell Medicine New York – Presbyterian Hospital and MD Anderson Blight Center to access approval of the revised protocols from their corresponding institutional assay boards in acclimation to resume accommodating enrollment.

UCART19: TALEN® gene-edited, allogeneic CAR T artefact applicant in ALL patients, alone accountant to Servier

Preliminary after-effects of the first-in-human analytic trials of UCART19 will be presented at the 59th American Society of Hematology anniversary affair (the “ASH Anniversary Meeting”) to be captivated from December 9 to 12, 2017 in Atlanta, GA. After-effects from the UCART19 analytic balloon in developed ALL patients will be presented orally by Reuben Benjamin, arch investigator for the balloon and adviser hematologist at King’s College Hospital, United Kingdom. After-effects from the UCART19 analytic balloon in pediatric ALL patients will be presented during a affiche affair by Waseem Qasim, arch investigator for the balloon and adviser in pediatric immunology and clairvoyant in corpuscle and gene assay at Great Ormond Street Hospital for Children, United Kingdom.

UCARTCS1, UCART22 & UCART123

Three abstracts apropos added Company’s off-the-shelf CAR T artefact candidates accept been accustomed for presentation at the 59th American Society of Hematology (ASH) Anniversary Meeting:

Corporate Governance

On October 4, 2017, Mathieu Simon M.D., Executive VP and Chief Operating Officer, as been appointed as Interim Chief Medical Officer. In accepting this position, Dr. Simon assumes the responsibilities of Loan Hoang-Sayag, who larboard Cellectis to accompany added able opportunities. Effective on October 11, 2017, Dr. Simon additionally accommodated from his position as a affiliate of the lath of admiral in acclimation to focus on his added responsibilities as Interim Chief Medical Officer.

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Calyxt, Inc. – Cellectis’ bulb science accessory

Articles

Calyxt’s herbicide-tolerant wheat, its third aureate artefact candidate, and bigger oil acceding canola, its aboriginal canola artefact candidate, accept avant-garde to Appearance 1 of development. With these appearance advancements, Calyxt now has a absolute of nine artefact candidates in Appearance 1 of development or afterwards above its bristles crops: soybeans, wheat, canola, potatoes and alfalfa.

The aboriginal of Calyxt’s two alfalfa artefact candidates has been appointed as a non-regulated commodity beneath the “Am I Regulated?” Action by Biotechnology Authoritative Services of the Animal and Bulb Health Inspection Service (APHIS), an bureau of the USDA. The bigger affection alfalfa is the sixth Calyxt artefact applicant to be accepted as a non-regulated commodity by the USDA including its aerial oleic soybean, aerial oleic / low linolenic soybean, arenaceous bane aggressive wheat, algid storable potatoes and bargain browning potatoes.

Corporate

Antecedent Accessible Offering: On July 25, 2017, Calyxt completed an antecedent accessible alms of its accepted stock, affairs an accumulated of 8,050,000 shares of accepted banal at a amount of $8.00 per allotment (including 1,050,000 shares of accepted banal pursuant to the exercise by the underwriters of their advantage to acquirement added shares). Calyxt accustomed net accretion of about $58.0 million, afterwards deducting underwriting discounts and commissions and alms expenses. As allotment of the IPO, Cellectis purchased 2,500,000 shares of accepted banal for a amount of $20.0 million, which is included in the net accretion that Calyxt received. Calyxt acclimated $5.7 actor of the accretion to awning a allocation of the outstanding obligations owed to Cellectis. Following Calyxt’s IPO, Cellectis owns 79.8% of the outstanding Calyxt’s accepted shares.

Auction Leaseback Transaction: On September 6, 2017, Calyxt consummated a sale-leaseback transaction including a charter acceding amid Calyxt and a third affair with account to the Calyxt’s charter of assertive absolute acreage and improvements amid in Roseville, Minnesota for a appellation of twenty years with advantage to extend the appellation for up to an added twenty years.

Abode Construction: Calyxt has burst arena on its new 40,000-square-foot headquarters, which will be housed on the 11-acre armpit in Roseville, calm with advanced assay completed about 11,000-square-foot greenhouses.

Banking After-effects

Cellectis’ circumscribed banking statements accept been able in accordance with International Banking Reporting Standards, or IFRS, as issued by the International Accounting Standards Lath (“GAAP”).

Effective in the third division of 2017, Cellectis afflicted the presentation bill of its circumscribed banking statements from the euro to the U.S. dollar, in acclimation to enhance allegory with peers, which primarily present their banking statements in U.S. dollar.

Third division 2017 Banking After-effects

Cash: As of September 30, 2017, Cellectis had $304.1 actor in absolute cash, banknote equivalents and accustomed banking assets compared to $271.2 actor as of June 30, 2017. This access of $32.9 actor reflects (i) an access of $38.0 actor attributable to Calyxt IPO, (ii) the net banknote provided by advance activities of $6.1 actor included $7.0 actor of accretion from Calyxt’s auction leaseback transaction and (iii) the abeyant absolute adaptation aftereffect of barter amount fluctuations on U.S. dollar cash, banknote equivalents and accustomed banking assets of $3.1 million; partially account by (iv) the net banknote flows acclimated by operating activities of $15.5 million.

Cellectis expects that its cash, banknote equivalents and accustomed banking assets of $304.1 actor as of September 30, 2017 will be acceptable to armamentarium its accustomed operations into 2020.

Revenues and Added Income: During the abode concluded September 30, 2016 and 2017, we recorded $12.6 actor and $7.3 million, respectively, in revenues and added income. This abatement of $5.4 actor is mainly due to (i) a $5.0 actor abatement in accord revenues of which $4.0 actor represented acquirement from payments by Servier during the division concluded September 30, 2016 for the accumulation of raw abstracts and batches of UCART19 products, that did not recur during the division concluded September 30, 2017, $0.6 actor represented decreased acceptance of upfront already paid to Cellectis and a $0.3 actor abatement in assay and development amount reimbursements, (ii) a $0.2 actor abatement in authorization acquirement and (iii) a $0.2 actor abatement in assay acclaim tax.

Absolute Operating Expenses: Absolute operating costs for the third division of 2017 were $33.0 million, compared to $25.5 actor for the third division of 2016. The non-cash stock-based advantage costs included in these amounts were $12.8 actor and $13.5 million, respectively.

R&D Expenses: For the abode concluded September 30, 2016 and 2017, assay and development costs added by $4.9 actor from $15.4 actor in 2016 to $20.3 actor in 2017. Cadre costs decreased by $2.1 actor from $10.3 actor in 2016 to $8.1 actor in 2017, primarily due to a $2.3 actor abatement in non-cash banal based advantage expense, partly account by a $0.2 actor access in accomplishment and salaries. Purchases and alien costs added by $6.8 actor from $4.9 actor in 2016 to $11.7 actor in 2017, mainly due to added costs accompanying to payments to third parties accommodating in artefact development, purchases of biological raw materials, costs for action development and costs associated with the use of laboratories and added facilities. Added costs added by $0.2 actor for the third division of 2017 compared to the third division of 2016.

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SG&A Expenses: During the abode concluded September 30, 2016 and 2017, we recorded $9.7 actor and $12.2 million, respectively, of selling, accustomed and authoritative expenses. The access of $2.4 actor primarily reflects an access of $2.2 actor in cadre costs from $7.4 actor to $9.6 million, attributable, amid added things, to an access of $0.5 in accomplishment and salaries and an access of $1.6 actor in non-cash stock-based advantage expense, as able-bodied as an access of $0.3 actor in purchases and alien expenses.

Banking Accretion (Loss): The banking accident was $1.2 actor for the third division of 2016 compared with a banking accident of $3.4 actor for the third division of 2017. The change in banking aftereffect was primarily attributable to an access in net adopted barter accident of $3.2 actor due to the aftereffect of barter amount fluctuations on our U.S. dollar banknote and banknote agnate accounts, partially account by an access of $0.8 actor in fair amount acclimation assets on our adopted barter derivatives and accustomed banking assets and an access of $0.2 actor in absorption accustomed from our banking investment.

Net Assets (Loss) Attributable to Shareholders of Cellectis: During the three months concluded September 30, 2016 and 2017, we recorded a net accident attributable to shareholders of Cellectis of $14.1 actor (or $0.40 per allotment on both a basal and a adulterated basis) and net accident attributable to shareholders of Cellectis of $26.2 actor (or $0.73 per share), respectively. Adapted accident attributable to shareholders of Cellectis for the third division of 2017 was $13.3 actor ($0.37 per share) compared to adapted accident attributable to shareholders of Cellectis of $0.5 actor ($0.02 per), for the third division of 2016. Adapted assets (loss) attributable to shareholders of Cellectis for the third division of 2017 and 2016 excludes non-cash stock-based advantage amount of $12.8 actor and $13.5 million, respectively. Please see “Note Apropos Use of Non-GAAP Banking Measures” for adaptation of GAAP net assets (loss) attributable to shareholders of Cellectis to adapted assets (loss) attributable to shareholders of Cellectis.

Aboriginal Nine Months 2017 Banking After-effects

Cash: As of September 30, 2017, Cellectis had $304.1 actor in absolute cash, banknote equivalents and accustomed banking assets compared to $ 291.2 actor as of December 31, 2016. This access of $12.9 actor primarily reflects (i) the accretion of $38.0 actor as allotment of the Calyxt IPO, (ii) the net banknote provided by advance activities of $2.3 actor which includes $7.0 actor of accretion from Calyxt’s auction leaseback transaction and (iii) the abeyant absolute adaptation aftereffect of barter amount fluctuations on U.S. dollar cash, banknote equivalents and accustomed banking assets of $13.1 million; partially account by the net banknote flows acclimated by operating activities of $42.8 million.

Revenues and Added Income: During the nine-month aeon concluded September 30, 2016 and 2017, we recorded $43.5 actor and $26.7 million, respectively, in revenues and added income. This abatement of $16.8 actor is mainly due to (i) a $16.9 actor abatement in accord revenues of which $8.5 actor represented ancient milestones revenues accustomed during the additional division of 2016 with the aboriginal accommodating dosed in the Appearance 1 analytic balloon for UCART 19, $4.8 actor represented decreased acceptance of upfront fees already paid to Cellectis and $1.5 actor represented abatement in assay and development amount reimbursements and $2.2 actor represented decreased acquirement from acquittal by Servier for the accumulation of raw abstracts and batches of UCART19 products, and (ii) a $0.4 actor abatement in added licenses revenue, partially account by (iii) an access of $0.5 actor in assay tax credits.

Absolute Operating Expenses: Total-operating costs for the nine-month aeon concluded September 30, 2017 were $91.8 million, compared to $90.3 actor for the nine months concluded September 30, 2016. The non-cash stock-based advantage costs included in these amounts were $38.9 actor and $44.5 million, respectively.

R&D Expenses: For the nine months concluded September 30, 2016 and 2017, assay and development costs added by $0.3 actor from $58.3 actor in 2016 to $58.5 actor in 2017. Cadre costs decreased by $8.5 actor from $36.4 actor in 2016 to $27.9 million in 2017, primarily due to a $6.7 actor abatement in non-cash banal based advantage expense, and a $1.9 million abatement in amusing accuse on banal options grants partly account by a $0.1 million access in accomplishment and salaries. Purchases and alien costs added by $8.4 actor from $20.7 actor in 2016 to $29.1 actor in 2017, mainly due to added costs accompanying to payments to third parties accommodating in artefact development, purchases of biological raw materials, costs for action development and costs associated with the use of laboratories and added facilities. Added costs added by $0.4 actor for the nine months concluded September 30, 2017 compared to the nine months concluded September 30, 2016.

SG&A Expenses: During the nine months concluded September 30, 2016 and 2017, we recorded $31.1 actor and $31.8 million, respectively, of selling, accustomed and authoritative expenses. The access of $0.8 actor primarily reflects (i) an access of $1.1 million in cadre costs from $23.9 million to $25.0 million, attributable to a $1.6 million access in accomplishment and salaries, a $1.1 actor access in non-cash banal based advantage expense, partly account by a abatement of $1.6 million of amusing accuse on banal options grants, (ii) a $0.2 access in added expenses, partially account by a $0.5 million abatement in purchases and alien expenses.

Banking Accretion (Loss): The banking accident was $7.1 actor for the nine months concluded September 30, 2016 compared with banking accident of $10.0 actor for the nine months concluded September 30, 2017. The change in banking aftereffect was primarily attributable to the aftereffect of barter amount fluctuations on our U.S. dollar banknote and banknote agnate accounts for $7.3 actor partially account by the fair amount acclimation on our acquired apparatus and banking accustomed asset for $4.2 actor and the absorption accustomed from our banking advance for $0.2 million.

Net Assets (Loss) Attributable to Shareholders of Cellectis: During the nine months concluded September 30, 2016 and 2017, we recorded a net accident attributable to shareholders of Cellectis of $53.9 actor (or $ 1.53 per share) and a net accident attributable to shareholders of Cellectis of $72.3 actor (or $2.03 per share), respectively. Adapted accident attributable to shareholders of Cellectis for the nine months concluded September 30, 2017 was $33.3 actor ($0.94 per share) compared to adapted accident attributable to shareholders of Cellectis of $9.4 actor ($0.27 per share), for the nine months concluded September 30, 2016. Adapted accident attributable to shareholders of Cellectis for the nine months concluded September 30, 2017 and 2016 excludes a non-cash stock-based advantage amount of $38.9 actor and $44.5 million, respectively. Please see “Note Apropos Use of Non-GAAP Banking Measures” for adaptation of GAAP net assets (loss) attributable to shareholders of Cellectis to adapted net assets (loss) attributable to shareholders of Cellectis.

CELLECTIS S.A.

 

INTERIM STATEMENT OF CONSOLIDATED FINANCIAL POSITION

($ in thousands, except per allotment data)

Audited

Non audited

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CELLECTIS S.A.

 

INTERIM STATEMENT OF CONSOLIDATED OPERATIONS – Third division

(unaudited)

($ in thousands, except per allotment data)

concluded September 30,

Basal net assets (loss) attributable to shareholders ofCellectis per allotment ($/share)

Adulterated net assets (loss) attributable to shareholders ofCellectis per allotment ($/share)

CELLECTIS S.A.

 

STATEMENT OF CONSOLIDATED OPERATIONS – FIRST NINE MONTHS

(unaudited)

($ in thousands, except per allotment data)

concluded September 30,

Attributable to non-controlling interests

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(2 788)

Basal net assets (loss) attributable to shareholders ofCellectis per allotment ($/share)

Adulterated net assets (loss) attributable to shareholders ofCellectis per allotment ($/share)

Note Apropos Use of Non-GAAP Banking Measures

Cellectis S.A. presents adapted net assets (loss) attributable to shareholders of Cellectis in this columnist release. Adapted net assets (loss) attributable to shareholders of Cellectis is not a admeasurement affected in accordance with IFRS. We accept included in this columnist absolution a adaptation of this amount to Net assets (loss) attributable to shareholders of Cellectis, which is the best anon commensurable banking admeasurement affected in accordance with IFRS. Because adapted net assets (loss) attributable to shareholders of Cellectis excludes Non-cash stock-based advantage expense—a non-cash expense, we accept that this banking measure, back advised calm with our IFRS banking statements, can enhance an all-embracing compassionate of Cellectis’ banking performance. Moreover, our administration angle the Company’s operations, and manages its business, based, in part, on this banking measure. In particular, we accept that the aishment of Non-cash stock-based costs from Net assets (loss) attributable to shareholders of Cellectis can accommodate a advantageous admeasurement for period-to-period comparisons of our amount businesses. Our use of adapted net assets (loss) attributable to shareholders of Cellectis has limitations as an analytic tool, and you should not accede it in a or as a acting for assay of our banking after-effects as appear beneath IFRS. Some of these limitations are: (a) added companies, including companies in our industry which use agnate stock-based compensation, may abode the appulse of Non-cash stock-based advantage amount differently; and (b) added companies may address adapted net assets (loss) attributable to shareholders or analogously blue-blooded measures but account them differently, which reduces their account as a allusive measure. Because of these and added limitations, you should accede adapted net assets (loss) attributable to shareholders of Cellectis alongside our IFRS banking results, including Net assets (loss) attributable to shareholders of Cellectis.

RECONCILIATION OF GAAP TO NON-GAAP NET INCOME – Third division

(unaudited)

($ in thousands, except per allotment data)

concluded September 30,

Net net assets (loss) attributable to shareholders ofCellectis

Non-cash stock-based advantage amount

Adapted net assets (loss) attributable to shareholdersof Cellectis

Basal Adapted net assets (loss) attributable toshareholders of Cellectis ($/share)

Weighted boilerplate cardinal of outstanding shares, basic(units)

Adulterated Adapted net assets (loss) attributable toshareholders of Cellectis ($/share)

Weighted boilerplate cardinal of outstanding shares,diluted (units)

RECONCILIATION OF GAAP TO NON-GAAP NET INCOME – Aboriginal nine months

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(unaudited)

($ in thousands, except per allotment data)

concluded September 30,

Net net assets (loss) attributable to shareholders ofCellectis

Non-cash stock-based advantage amount

Adapted net assets (loss) attributable to shareholdersof Cellectis

Basal Adapted net assets (loss) attributable toshareholders of Cellectis ($/share)

Weighted boilerplate cardinal of outstanding shares, basic(units)

Adulterated Adapted net assets (loss) attributable toshareholders of Cellectis ($/share)

Weighted boilerplate cardinal of outstanding shares,diluted (units)

About Cellectis

Cellectis is a clinical-stage biopharmaceutical aggregation focused on developing a new bearing of blight immunotherapies based on gene-edited T-cells (UCART). By capitalizing on its 17 years of ability in gene alteration – congenital on its flagship TALEN® technology and beat electroporation arrangement PulseAgile – Cellectis uses the ability of the allowed arrangement to ambition and eradicate blight cells. Using its life-science-focused, beat genome engineering technologies, Cellectis’ ambition is to actualize avant-garde articles in assorted fields and with assorted ambition markets. Cellectis is listed on the Nasdaq bazaar (ticker: CLLS) and on the NYSE Euronext Growth bazaar (ticker: ALCLS). To acquisition out added about us, appointment our website: www.cellectis.com

Talking about gene editing? We do it. TALEN® is a registered brand endemic by Cellectis.

Cautionary Statement Apropos Forward-Looking Statements

This columnist absolution contains assertive “forward – attractive statements” aural the acceptation of the Private Securities Litigation Reform Act of 1995. Advanced statements may be articular by words such as “anticipate,” “believe,” “can,” “could,” “estimate,” “expect,” “intend,” “is advised to,” “may,” “might,” “plan,” “potential,” “predict,” “objective,” “should,” or the abrogating of these and agnate expressions and include, but are not bound to, statements apropos the angle for Cellectis’ approaching business and banking performance. Advanced statements are based on management’s accustomed expectations and assumptions, which are accountable to inherent uncertainties, risks and changes in circumstances, abounding of which are above Cellectis’ control. Actual outcomes and after-effects may alter materially due to all-around political, economic, business, competitive, market, authoritative and added factors and risks. Cellectis especially disclaims any obligation to amend or alter any of these advanced statements, whether because of approaching events, new information, a change in its angle or expectations, or otherwise.

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